منابع مشابه
Brain myosin-V is a two-headed unconventional myosin with motor activity.
Chicken myosin-V is a member of a recently recognized class of myosins distinct from both the myosins-I and the myosins-II. We report here the purification, electron microscopic visualization, and motor properties of a protein of this class. Myosin-V molecules consist of two heads attached to an approximately 30 nm stalk that ends in a globular region of unknown function. Myosin-V binds to and ...
متن کاملMyosin-IXb is a single-headed and processive motor.
Class IX myosins are unique among the many classes of known actin-based motors in that the tail region of these myosins contains a GTPase-activating protein domain for the small GTP-binding protein, Rho. Previous studies on human myosin-IXb indicate that this myosin is mechanochemically active and exhibits actin-binding properties similar to the processive motor, myosin-Va. Motility analysis of...
متن کاملHybrid four-headed myosin motor engineered with antagonistic motor domains.
B idirectional, or saltatory, motion is the back-and-forth movement of organelles as they are transported on their filamentous tracks (1, 2). It occurs when plus-end– and minus-end–directed motor proteins colocate on a cargo and there is an alternation in which motor dominates. Bidirectional transport has been observed for many organelles—exosomes, endosomes, mitochondria, melanosomes, neural a...
متن کاملMyosin V motor proteins
Mammalian myosin V motors transport cargo processively along actin filaments. Recent biophysical and structural studies have led to a detailed understanding of the mechanism of myosin V, making it perhaps the best understood cytoskeletal motor. In addition to describing the mechanism, this review will illustrate how "dynamic" single molecule measurements can synergize with "static" protein stru...
متن کاملToxoplasma gondii myosin A and its light chain: a fast, single-headed, plus-end-directed motor.
Successful host cell invasion is a prerequisite for survival of the obligate intracellular apicomplexan parasites and establishment of infection. Toxoplasma gondii penetrates host cells by an active process involving its own actomyosin system and which is distinct from induced phagocytosis. Toxoplasma gondii myosin A (TgMyoA) is presumed to achieve power gliding motion and host cell penetration...
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ژورنال
عنوان ژورنال: Seibutsu Butsuri
سال: 2001
ISSN: 0582-4052,1347-4219
DOI: 10.2142/biophys.41.s191_1